Mean Index Scores

Fryback, D.G., Dunham, N.C., Palta, M., Hanmer, J., Buechner, J., Cherepanov, D., Herrington, S.A., Hays, R.D., Kaplan, R.M., Ganiats, T.G., Feeny, D., Kind, P., U.S. Norms for Six Generic Health-Related Quality-of-Life Indexes From the National Health Measurement Study. Medical Care, December 2007.

Work In Progress

Health-related Quality of Life (HRQoL) and Obesity

Dunham et al.

Above: Distribution of obesity within the NHMS participants
Below: Differences in mean scores seem to be more pronounced in women with obesity compared to men

HRQoL and COPD

Mularski et al.
Across all 4 instruments (EQ-5D, QWB, HUI 2/3, SF-6D), respondents with COPD (n = 279) had significantly lower HRQoL scores ranging from 0.52 - 0.74 compared to 0.72 - 0.93 for healthy individuals (n = 995, p < 0.001). Mean scores in COPD were also lower than those with diabetes (n = 631; differences -0.05 to -0.08, p < 0.01). Modeling identified depression and sleep disorders as having significant independent associations with decreased HRQoL across all 4 instruments. Preference-based HRQoL measures documented a substantial burden of disease for adults with COPD. We confirmed independent contributions of disease co-morbidity, particularly sleep disorders and depression, to reductions in health utility for those with COPD.

Above: Differences in mean scores most striking in younger age groups
Below: QALYs lost each year due to COPD

HRQoL and Gender Differences

Cherepanov et al.

Below: Mean scores for women always seem to be lower than for men

HRQoL and Socioeconomic Status

Robert et al.
At every age, significant differences in HRQoL are associated with income, education and assets (each has an independent association). Education and income differentials in HRQoL are relatively consistent across adult age groups controlling for other SES measures, race, and gender. HRQoL differentials associated with household assets are widest through midlife into old age.